| http://purl.uniprot.org/citations/18390200 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18390200 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo study the gene polymorphisms of position --2123 C/G,--1969 G/A,--1817 T/C in promoter region and of Thr715Pro in exon thirteenth of P-selectin in the Chinese Han of Chengdu and Thai populations, and simultaneously to compare distributions of genotype and allelic frequencies of P-selectins among different races. Methods The genotypes and allele frequencies of the P-selectin base --2123 C/G,--1969 G/A,-1817 T/C and amino acid Thr715Pro were detected by polymerase chain reaction -restriction fragment length polymorphism (PCR-RFLP) to 120 healthy Chinese Han of Chengdu and 110 Thai population.ResultsThere were no significant differences in the genotype and allele distribution of--2123 C/G,--1969 G/A,--1817 T/C polymorphisms for the P-selectin gene between Chinese Han of Chengdu and Thai populations (P > 0.05), in which compared with England and American, the distribution of P-selectin genotype and allele had significantly differences among ethnics (P < 0.001). No polymorphism of Thr715Pro was found in this study. Conclusion In Chinese Han of Chengdu and Thai populations the polymorphisms exist at base position--2123 C/G,--1969 G/A and --1817 T/C in promoter region of P-selectin. There are no significant differences in the genotype and allele distribution of the P-selectin gene polymorphisms between Chinese Han of Chengdu and Thai populations, but significantly different distribution of P-selectin gene polymorphisms occur among ethnics."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Yang Z.H."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Lu M.L."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Zhu Y.H."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Wei Y.S."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Tai S.H."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Liang W.B."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/author | "Gao L.B."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/name | "Sichuan Da Xue Xue Bao Yi Xue Ban"xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/pages | "55-58"xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/title | "[Study on genetic polymorphisms of P-selectins in Chinese Han of Chengdu and Thai populations]."xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://purl.uniprot.org/core/volume | "39"xsd:string |
| http://purl.uniprot.org/citations/18390200 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18390200 |
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