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http://purl.uniprot.org/citations/18397187http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18397187http://www.w3.org/2000/01/rdf-schema#comment"The human leukocyte antigen (HLA) system could play an essential role in multiple myeloma (MM) disease control. This report describes the results comparing HLA-DRB1 phenotypic frequencies in 181 MM patients (53 smoldering/indolent MM and 128 symptomatic MM patients) and healthy individuals. Higher DRB1*01 phenotypic frequencies were found in the smoldering patients compared with symptomatic MM patients (38% vs 14%, P = 0.001) and with the healthy individuals (38% vs 22%, P = 0.01). Additionally, higher DRB1*07 phenotypic frequencies were found in symptomatic MM compared with control population (38% vs 28%, P = 0.01). The present data suggest that HLA-DRB1*01 individuals may have a better ability to efficiently present myeloma-related antigens to immunocompetent cells, which could favor a better immune response against the tumor. This would translate into a more appropriate disease control associated with more indolent disease and prolonged survival."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.org/dc/terms/identifier"doi:10.1111/j.1399-0039.2008.01048.x"xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Gonzalez M."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Hernandez J.M."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"San Miguel J.F."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Marin L."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Corral R."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Balanzategui A."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Garcia-Sanz R."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Chillon M.C."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Alcoceba M."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Blade J."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Fernandez-Calvo F.J."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Lahuerta J.J."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Martin-Jimenez P."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Perez-Persona E."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/author"Sarasquete M.E."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/name"Tissue Antigens"xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/pages"548-551"xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/title"The presence of DRB1*01 allele in multiple myeloma patients is associated with an indolent disease."xsd:string
http://purl.uniprot.org/citations/18397187http://purl.uniprot.org/core/volume"71"xsd:string
http://purl.uniprot.org/citations/18397187http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18397187
http://purl.uniprot.org/citations/18397187http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/18397187