DESCRIBE <http://purl.uniprot.org/citations/18402948>

Subject	Predicate	Object
http://purl.uniprot.org/citations/18402948	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18402948	http://www.w3.org/2000/01/rdf-schema#comment	" Objective To describe the case of isolated follicle-stimulating hormone (FSH) deficiency without mutation of the FSHbeta gene. Design Case report. Setting Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan. Patient(s) A 22-year-old man referred for infertility, azoospermia, and isolated FSH deficiency. Intervention(s) The patient's FSHbeta gene was sequenced. Pituitary function at baseline and after repeated GnRH administration was evaluated. Testicular biopsy was performed. The patient was treated with human menopausal gonadotropin (hMG). Main outcome measure(s) Pathologic examination revealed hypospermatogenesis with isolated FSH deficiency without mutation of the FSHbeta gene. Result(s) The FSH levels remained below the normal range despite repeated GnRH stimulation. Hypospermatogenesis was confirmed by testicular biopsy. After 6 months of hMG treatment, spermatogenesis was successfully induced. Conclusion(s) We report the case of an infertile male with isolated FSH deficiency without any evidence of mutation in the FSHbeta gene."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.org/dc/terms/identifier	"doi:10.1016/j.fertnstert.2008.02.145"xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Imachi H."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Ishida T."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Fujiwara M."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Murao K."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Kushida Y."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Haba R."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/author	"Muraoka T."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/date	"2008"xsd:gYear
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/name	"Fertil Steril"xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/pages	"2012.e17-9"xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/title	"Isolated follicle-stimulating hormone (FSH) deficiency without mutation of the FSHbeta gene and successful treatment with human menopausal gonadotropin."xsd:string
http://purl.uniprot.org/citations/18402948	http://purl.uniprot.org/core/volume	"90"xsd:string
http://purl.uniprot.org/citations/18402948	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/18402948
http://purl.uniprot.org/citations/18402948	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/18402948
http://purl.uniprot.org/uniprot/#_A0A0F7RQE8-mappedCitation-18402948	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/#_Q27RP3-mappedCitation-18402948	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/#_P01225-mappedCitation-18402948	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/#_Q1W658-mappedCitation-18402948	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/Q27RP3	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/A0A0F7RQE8	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/P01225	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/18402948
http://purl.uniprot.org/uniprot/Q1W658	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/18402948