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http://purl.uniprot.org/citations/18460953http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18460953http://www.w3.org/2000/01/rdf-schema#comment"

Background

Early identification of acute coronary syndrome (ACS) in the emergency room is still a difficult task. The objective of this study is to estimate the reliability of heart-type fatty acid binding protein (H-FABP) in identifying ACS in the early stage of chest pain onset.

Methods

In a prospective multicentre study in emergency room patients with suspected ACS lasting less than 3 h, heart heart-type fatty acid binding protein (H-FABP) was compared with conventional biomarkers. Protein levels >7 ng/ml were considered positive results.

Results

A total of 419 patients were analyzed. Acute myocardial infarction was diagnosed in 148 patients (35%). H-FABP sensitivity was 60% (89 out of 148 patients), significantly higher than troponin T [19% (28 out of 148 patients); P<0,05]. Specificity of troponin T, however, [99% (270 out of 271 patients)] was better than H-FABP [88% (237 out of 271 patients)], though this was not statistically significant.

Conclusion

H-FABP can be a useful early diagnostic biochemical marker, particularly within the first 6 h of symptoms, in patients attending the emergency department."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.org/dc/terms/identifier"doi:10.1097/mej.0b013e3282efd47a"xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/author"Sanchez M.S."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/author"Bel M.S."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/author"Gonzalo F.E."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/author"Oliva L.I."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/author"Riesgo L.G."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/author"Valle H.A."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/name"Eur J Emerg Med"xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/pages"140-144"xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/title"Clinical assessment of heart-type fatty acid binding protein in early diagnosis of acute coronary syndrome."xsd:string
http://purl.uniprot.org/citations/18460953http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/18460953http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18460953
http://purl.uniprot.org/citations/18460953http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/18460953
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