| http://purl.uniprot.org/citations/18502870 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18502870 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18502870 | http://www.w3.org/2000/01/rdf-schema#comment | "High-affinity iron acquisition in Bacillus subtilis is mediated via the bacillibactin catechole siderophore pathway. Three of the four essential pathway steps, bacillibactin synthesis, Fe-bacillibactin uptake, and Fe-bacillibactin hydrolysis have been characterized previously. The functional and regulatory components for bacillibactin secretion, the second step of the siderophore pathway, remained unknown. In this study, the screening of a B. subtilis exporter mutant library led to the identification of the YmfE major facilitator superfamily (MFS)-type transporter as a target for bacillibactin export. Analysis of iron-limited ymfE mutant cultures displayed an eightfold reduced bacillibactin secretion and, on the other hand, a 25-fold increased secretion of the bacillibactin precursor 2,3-dihydroxybenzoate. Investigation of the regulatory aspect revealed that bacillibactin secretion is, in contrast to all other components of the pathway, independent of the ferric uptake repressor Fur. Indeed, the MerR-type transcriptional regulator Mta was found to activate both bacillibactin secretion and ymfE gene expression, exposing Mta as an additional regulatory member of the bacillibactin pathway."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.00464-08"xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.00464-08"xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/author | "Schmidt S."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/author | "Schmidt S."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/author | "Marahiel M.A."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/author | "Marahiel M.A."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/author | "Miethke M."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/author | "Miethke M."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/pages | "5143-5152"xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/pages | "5143-5152"xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/title | "The major facilitator superfamily-type transporter YmfE and the multidrug-efflux activator Mta mediate bacillibactin secretion in Bacillus subtilis."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/title | "The major facilitator superfamily-type transporter YmfE and the multidrug-efflux activator Mta mediate bacillibactin secretion in Bacillus subtilis."xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/volume | "190"xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://purl.uniprot.org/core/volume | "190"xsd:string |
| http://purl.uniprot.org/citations/18502870 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18502870 |
| http://purl.uniprot.org/citations/18502870 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18502870 |
| http://purl.uniprot.org/citations/18502870 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18502870 |
| http://purl.uniprot.org/citations/18502870 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18502870 |