| http://purl.uniprot.org/citations/18516038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18516038 | http://www.w3.org/2000/01/rdf-schema#comment | "The cellular basis of immunological memory remains a controversial issue. Here we show that basophils bound large amounts of intact antigens on their surface and were the main source of interleukins 6 and 4 in the spleen and bone marrow after restimulation with a soluble antigen. Depletion of basophils resulted in a much lower humoral memory response and greater susceptibility of immunized mice to sepsis induced by Streptococcus pneumoniae. Adoptive transfer of antigen-reactive basophils significantly increased specific antibody production, and activated basophils, together with CD4(+) T cells, profoundly enhanced B cell proliferation and immunoglobulin production. These basophil-dependent effects on B cells required interleukins 6 and 4 and increased the capacity of CD4(+) T cells to provide B cell help. Thus, basophils are important contributors to humoral memory immune responses."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni.1621"xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Briles D.E."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Hollingshead S."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Moll C."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Winter C."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Mack M."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Kunz-Schughart L.A."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Niedermeier M."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Denzel A."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Maus R."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Maus U.A."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Rodriguez Gomez M."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/author | "Talke Y."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/pages | "733-742"xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/title | "Basophils enhance immunological memory responses."xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/18516038 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18516038 |
| http://purl.uniprot.org/citations/18516038 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18516038 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JGF4-mappedCitation-18516038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18516038 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YXC5-mappedCitation-18516038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18516038 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVS1-mappedCitation-18516038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18516038 |