| http://purl.uniprot.org/citations/18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18524595 | http://www.w3.org/2000/01/rdf-schema#comment | "To ensure the accuracy of gene expression, eukaryotes have evolved several surveillance mechanisms. One of the best-studied quality control mechanisms is nonsense-mediated mRNA decay (NMD), which recognizes and degrades transcripts harboring a premature translation-termination codon (PTC), thereby preventing the production of faulty proteins. NMD regulates approximately 10% of human mRNAs, and its physiological importance is manifested by the fact that approximately 30% of disease-associated mutations generate PTCs. Although different mechanisms of PTC recognition have been proposed for different species, recent studies in Saccharomyces cerevisiae, Drosophila melanogaster, Caenorhabditis elegans, plants and mammals suggest a conserved model. Here, we summarize the latest results and discuss an emerging model for NMD and its implications for the regulation of gene expression."xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.tcb.2008.04.005"xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/author | "Muhlemann O."xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/author | "Stalder L."xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/name | "Trends Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/pages | "315-321"xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/title | "The meaning of nonsense."xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/18524595 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18524595 |
| http://purl.uniprot.org/citations/18524595 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18524595 |
| http://purl.uniprot.org/uniprot/#_P61353-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P61513-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P61927-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_O15234-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P49207-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P39019-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P39023-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P42677-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P42766-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P52298-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P62495-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P62701-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |
| http://purl.uniprot.org/uniprot/#_P62750-mappedCitation-18524595 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18524595 |