| http://purl.uniprot.org/citations/18571877 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18571877 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18571877 | http://www.w3.org/2000/01/rdf-schema#comment | "We present herein a new model for the structure of the Drosophila kayak gene as well as preliminary data on the functional differences of its various isoforms. kayak is a homolog of the human proto-oncogene, c-fos. kayak has three different starts of transcription, and therefore promoters (P)kay-alpha, (P)kay-beta and (P)kay-gamma. These three promoters lead to four different transcripts: kay-alpha, kay(sro), kay-beta and kay-gamma. (P)kay-alpha produces two different transcripts: kay-alpha and kay(sro) where the other two promoters, (P)kay-beta and (P)kay-gamma, produce a single transcript each. The transcripts kay-alpha, beta and gamma all splice into the mainbody of the kay gene, which codes for the DNA binding domain and leucine zipper; kay(sro) is not spliced. Also, within this region is a nested gene, fos-intronic gene (fig) which is transcribed in the opposite direction. fig codes for a predicted PP2C phosphatase. fig has two different promoters which produce two different transcripts, both in the same reading frame, fig-alpha and beta. This is an unusual gene structure for Drosophila. Only 13% of Drosophila genes have multiple promoters and only 7% have a nested gene. RT-PCR was performed on each transcript to determine the relative amounts of each RNA produced. All spliced kay transcripts appear to have equal abundance. The unspliced kay(sro) transcript has a lower abundance than kay-alpha. Both fig transcripts are also detected in all stages tested. Lethal phase analysis and complementation testing suggest that the three isoforms of kayak may have different functions."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.gene.2008.05.001"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.gene.2008.05.001"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/author | "Goldstein E.S."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/author | "Goldstein E.S."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/author | "Hudson S.G."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/author | "Hudson S.G."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/pages | "76-81"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/pages | "76-81"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/title | "The gene structure of the Drosophila melanogaster proto-oncogene, kayak, and its nested gene, fos-intronic gene."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/title | "The gene structure of the Drosophila melanogaster proto-oncogene, kayak, and its nested gene, fos-intronic gene."xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/volume | "420"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://purl.uniprot.org/core/volume | "420"xsd:string |
| http://purl.uniprot.org/citations/18571877 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18571877 |
| http://purl.uniprot.org/citations/18571877 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18571877 |
| http://purl.uniprot.org/citations/18571877 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18571877 |
| http://purl.uniprot.org/citations/18571877 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18571877 |
| http://purl.uniprot.org/uniprot/A8MPH9 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/18571877 |
| http://purl.uniprot.org/uniprot/P21525 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/18571877 |