| http://purl.uniprot.org/citations/18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18596689 | http://www.w3.org/2000/01/rdf-schema#comment | "At termination of protein synthesis, type I release factors promote hydrolysis of the peptidyl-transfer RNA linkage in response to recognition of a stop codon. Here we describe the crystal structure of the Thermus thermophilus 70S ribosome in complex with the release factor RF1, tRNA and a messenger RNA containing a UAA stop codon, at 3.2 A resolution. The stop codon is recognized in a pocket formed by conserved elements of RF1, including its PxT recognition motif, and 16S ribosomal RNA. The codon and the 30S subunit A site undergo an induced fit that results in stabilization of a conformation of RF1 that promotes its interaction with the peptidyl transferase centre. Unexpectedly, the main-chain amide group of Gln 230 in the universally conserved GGQ motif of the factor is positioned to contribute directly to peptidyl-tRNA hydrolysis."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature07115"xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/author | "Laurberg M."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/author | "Noller H.F."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/author | "Trakhanov S."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/author | "Asahara H."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/author | "Korostelev A."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/pages | "852-857"xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/title | "Structural basis for translation termination on the 70S ribosome."xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://purl.uniprot.org/core/volume | "454"xsd:string |
| http://purl.uniprot.org/citations/18596689 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18596689 |
| http://purl.uniprot.org/citations/18596689 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18596689 |
| http://purl.uniprot.org/uniprot/#_P61941-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62613-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62652-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62653-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62654-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62655-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62656-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62657-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |
| http://purl.uniprot.org/uniprot/#_P62658-mappedCitation-18596689 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18596689 |