| http://purl.uniprot.org/citations/18619963 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18619963 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18619963 | http://www.w3.org/2000/01/rdf-schema#comment | "The nuclear hormone receptors (NHRs), a family of transcription factors, bind directly to the hormone response elements (HREs) to regulate gene expression. In this study, we describe a comprehensive NHR-HRE profiling analysis with a new high-throughput DNA binding assay system utilizing wheat germ cell-free protein production and fluorescence correlation spectroscopy (FCS). This approach revealed NHR binding to natural response elements and new heterodimeric NHR-HRE bindings. We analyzed 408 possible binding combinations between 34 human NHRs and 12 different HREs, and identified 205 NHR-HRE binding combinations, 124 of which have not been previously reported. Thus, this study provides a novel biochemical classification of the human NHRs, as well as describing a novel approach to the large-scale analysis of DNA-protein interactions."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2008.07.003"xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2008.07.003"xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Kobayashi T."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Kobayashi T."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Endo Y."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Endo Y."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Sawasaki T."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Sawasaki T."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Nozawa A."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Nozawa A."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Kodani Y."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/author | "Kodani Y."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/pages | "2737-2744"xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/pages | "2737-2744"xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/title | "DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/title | "DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system."xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/volume | "582"xsd:string |
| http://purl.uniprot.org/citations/18619963 | http://purl.uniprot.org/core/volume | "582"xsd:string |