http://purl.uniprot.org/citations/18648372 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18648372 | http://www.w3.org/2000/01/rdf-schema#comment | "Hypoxia inducible factor 1 (HIF-1) represses the transcription of pro-apoptotic bid in colorectal cancer cells in vitro. To assess the clinical relevance of this observation, HIF-1alpha and Bid were assessed in serial sections of 39 human colorectal adenocarcinomas by immunohistochemistry. In high HIF-1alpha nuclear-positive cell subpopulations, there was a significant reduction in Bid expression (ANOVA, P=0.04). Given the role of Bid in drug-induced apoptosis, these data add impetus to strategies targeting HIF-1 for therapeutic gain."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.bjc.6604474"xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Roberts D."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Dive C."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "O'Dwyer S.T."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Stratford I.J."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Renehan A.G."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Saunders M.P."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Cawthorne C."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Armstrong G.R."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/author | "Seenath M.M."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/name | "Br J Cancer"xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/pages | "459-463"xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/title | "Reciprocal relationship between expression of hypoxia inducible factor 1alpha (HIF-1alpha) and the pro-apoptotic protein bid in ex vivo colorectal cancer."xsd:string |
http://purl.uniprot.org/citations/18648372 | http://purl.uniprot.org/core/volume | "99"xsd:string |
http://purl.uniprot.org/citations/18648372 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18648372 |
http://purl.uniprot.org/citations/18648372 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18648372 |
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http://purl.uniprot.org/uniprot/#_B1PL87-mappedCitation-18648372 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18648372 |