http://purl.uniprot.org/citations/18663611 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18663611 | http://www.w3.org/2000/01/rdf-schema#comment | "Prostate cancer is the most common type of solid tumor and a leading cause of cancer-related death of men living in the developed world. In recent years, the molecular mechanisms involved in prostate cancer development and/or progression have been intensely studied and several genes have been identified. TGIFLX/Y (TGIFLX and TGIFLY) are members of the homeobox superfamily of genes whose function(s) is unknown. To investigate TGIFLX/Y mRNA expression in prostate cancer, we studied two different types of clinical samples, namely 60 prostate tumors and 15 cases of benign prostate hyperplasia (BPH), by RT-PCR. Our results revealed that most prostate tumors (73.5%) express at least one of these genes, although different patterns of TGIFLX/Y mRNA expression were observed. In some tumor samples the expression of both genes was detected, while in others no expression of either gene was observed. Notably, there was a significant correlation between expression of both TGIFLX and TGIFLY and a Gleason score of >or=6 (P = 0.038). By contrast, expression of TGIFLX/Y mRNA in BPH samples could not be detected. These results suggest an association of TGIFLX/Y expression with the progression of prostate cancer."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.org/dc/terms/identifier | "doi:10.1007/s12032-008-9086-7"xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Heidari M."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Greene W.K."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Raoofian R."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Ayati M."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Modarresi M.H."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Ousati Ashtiani Z."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/author | "Sabah Goulian B."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/name | "Med Oncol"xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/pages | "73-77"xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/title | "Association of TGIFLX/Y mRNA expression with prostate cancer."xsd:string |
http://purl.uniprot.org/citations/18663611 | http://purl.uniprot.org/core/volume | "26"xsd:string |
http://purl.uniprot.org/citations/18663611 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18663611 |
http://purl.uniprot.org/citations/18663611 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18663611 |
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