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http://purl.uniprot.org/citations/18667529http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18667529http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18667529http://www.w3.org/2000/01/rdf-schema#comment"The Arabidopsis MAP65s are a protein family with similarity to the microtubule-associated proteins PRC1/Ase1p that accumulate in the spindle midzone during late anaphase in mammals and yeast, respectively. Here we investigate the molecular and functional properties of AtMAP65-5 and improve our understanding of AtMAP65-1 properties. We demonstrate that, in vitro, both proteins promote the formation of a planar network of antiparallel microtubules. In vivo, we show that AtMAP65-5 selectively binds the preprophase band and the prophase spindle microtubule during prophase, whereas AtMAP65-1-GFP selectively binds the preprophase band but does not accumulate at the prophase spindle microtubules that coexists within the same cell. At later stages of mitosis, AtMAP65-1 and AtMAP65-5 differentially label the late spindle and phragmoplast. We present evidence for a mode of action for both proteins that involves the binding of monomeric units to microtubules that "zipper up" antiparallel arranged microtubules through the homodimerization of the N-terminal halves when adjacent microtubules encounter."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.org/dc/terms/identifier"doi:10.1091/mbc.e08-04-0341"xsd:string
http://purl.uniprot.org/citations/18667529http://purl.org/dc/terms/identifier"doi:10.1091/mbc.e08-04-0341"xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Gaillard J."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Gaillard J."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Neumann E."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Neumann E."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Geelen D."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Geelen D."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Van Damme D."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Van Damme D."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Ebel C."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Ebel C."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Vantard M."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Vantard M."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Stoppin-Mellet V."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Stoppin-Mellet V."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Barbier E."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/author"Barbier E."xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/name"Mol. Biol. Cell"xsd:string
http://purl.uniprot.org/citations/18667529http://purl.uniprot.org/core/name"Mol. Biol. Cell"xsd:string