| http://purl.uniprot.org/citations/18689444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18689444 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18689444 | http://www.w3.org/2000/01/rdf-schema#comment | "In plants, fatty acids are de novo synthesized predominantly in plastids from acetyl-coenzyme A. Although fatty acid biosynthesis has been biochemically well studied, little is known about the regulatory mechanisms of the pathway. Here, we show that overexpression of the Arabidopsis (Arabidopsis thaliana) LEAFY COTYLEDON1 (LEC1) gene causes globally increased expression of fatty acid biosynthetic genes, which are involved in key reactions of condensation, chain elongation, and desaturation of fatty acid biosynthesis. In the plastidial fatty acid synthetic pathway, over 58% of known enzyme-coding genes are up-regulated in LEC1-overexpressing transgenic plants, including those encoding three subunits of acetyl-coenzyme A carboxylase, a key enzyme controlling the fatty acid biosynthesis flux. Moreover, genes involved in glycolysis and lipid accumulation are also up-regulated. Consistent with these results, levels of major fatty acid species and lipids were substantially increased in the transgenic plants. Genetic analysis indicates that the LEC1 function is partially dependent on ABSCISIC ACID INSENSITIVE3, FUSCA3, and WRINKLED1 in the regulation of fatty acid biosynthesis. Moreover, a similar phenotype was observed in transgenic Arabidopsis plants overexpressing two LEC1-like genes of Brassica napus. These results suggest that LEC1 and LEC1-like genes act as key regulators to coordinate the expression of fatty acid biosynthetic genes, thereby representing promising targets for genetic improvement of oil production plants."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.org/dc/terms/identifier | "doi:10.1104/pp.108.126342"xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.org/dc/terms/identifier | "doi:10.1104/pp.108.126342"xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Chong K."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Chong K."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Fu F."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Fu F."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Liang Y."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Liang Y."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Mu J."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Mu J."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Yang X."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Yang X."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Wang T."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Wang T."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Zheng Q."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Zheng Q."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Zuo J."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Zuo J."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Tan H."xsd:string |
| http://purl.uniprot.org/citations/18689444 | http://purl.uniprot.org/core/author | "Tan H."xsd:string |