| http://purl.uniprot.org/citations/18755860 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18755860 | http://www.w3.org/2000/01/rdf-schema#comment | "To determine whether killer cell immunologlobulin-like receptor (KIR) genotypes are associated with vasculitis, vascular arterial events or anticardiolipin (aCL) antibodies in patients with lupus. A total of 304 patients followed prospectively at the University of Toronto Lupus Clinic were assessed for the occurrence of vasculitis and vascular arterial events. Molecular HLA-C and KIR (presence or absence of KIR2DL1, 2DL2, 2DL3, 2DS1 and 2DS2) genotyping were performed. Chi-square and logistic regression were used to analyse association between KIR genes and vascular arterial events and aCL antibodies. In patients with vascular arterial events, there was a significant increase in KIR2DS2 (60% vs 45%, P = 0.02) and in KIR2DL2 (62% vs 47%, P = 0.01) compared with patients without events. There was no increase in activating KIR genotypes in patients with vasculitis. In patients with aCL antibodies, significant increases were seen in KIR2DS2 (54% vs 41%, P = 0.03) and KIR2DL2 (58% vs 41%, P = 0.003), but KIR2DL3 was decreased (87% vs 95%, P = 0.03). Logistic regression confirmed independent association of KIR2DS2 with vascular arterial events. We found an increase in KIR2DS2 in lupus patients with vascular arterial events, but not in patients with vasculitis."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.org/dc/terms/identifier | "doi:10.1177/0961203308089443"xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/author | "Chandran V."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/author | "Gladman D."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/author | "Pellett F."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/author | "Urowitz M."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/author | "Ibanez D."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/author | "Toloza S."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/name | "Lupus"xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/pages | "793-798"xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/title | "Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus."xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/18755860 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18755860 |
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| http://purl.uniprot.org/uniprot/#_A0A1W2PRZ1-mappedCitation-18755860 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18755860 |
| http://purl.uniprot.org/uniprot/#_A0A1W2PSB7-mappedCitation-18755860 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18755860 |
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