| http://purl.uniprot.org/citations/18761673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18761673 | http://www.w3.org/2000/01/rdf-schema#comment | "Myo18B is an unconventional myosin family protein expressed predominantly in muscle cells. Although conventional myosins are known to be localized on the A-bands and function as a molecular motor for muscle contraction, Myo18B protein was localized on the Z-lines of myofibrils in striated muscles. Like Myo18A, another 18th class of myosin, the N-terminal unique domain of the protein and not the motor domain and the coiled-coil tail is critical for its localization to F-actin in myocytes. Myo18B expression was induced by myogenic differentiation through the binding of myocyte-specific enhancer factor-2 to its promoter. Deficiency of Myo18B caused an embryonic lethality in mice accompanied by disruption of myofibrillar structures in cardiac myocytes at embryonic day 10.5. Thus, Myo18B is a unique unconventional myosin that is predominantly expressed in myocytes and whose expression is essential for the development and/or maintenance of myofibrillar structure."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2443.2008.01226.x"xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Kohno T."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Yokota J."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Kodama M."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Akazawa H."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Komuro I."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Takeshita F."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Ochiya T."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Ajima R."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/author | "Otsuka A."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/name | "Genes Cells"xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/pages | "987-999"xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/title | "Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrations."xsd:string |
| http://purl.uniprot.org/citations/18761673 | http://purl.uniprot.org/core/volume | "13"xsd:string |
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