| http://purl.uniprot.org/citations/18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18769915 | http://www.w3.org/2000/01/rdf-schema#comment | "Human leukocyte antigen class I (HLA-I) molecules are highly polymorphic peptide receptors, which select and present endogenously derived peptide epitopes to CD8+ cytotoxic T cells (CTL). The specificity of the HLA-I system is an important component of the overall specificity of the CTL immune system. Unfortunately, the large and rapidly increasing number of known HLA-I molecules seriously complicates a comprehensive analysis of the specificities of the entire HLA-I system (as of June 2008, the international HLA registry holds >1,650 unique HLA-I protein entries). In an attempt to reduce this complexity, it has been suggested to cluster the different HLA-I molecules into "supertypes" of largely overlapping peptide-binding specificities. Obviously, the HLA supertype concept is only valuable if membership can be assigned with reasonable accuracy. The supertype assignment of HLA-A*3001, a common HLA haplotype in populations of African descent, has variously been assigned to the A1, A3, or A24 supertypes. Using a biochemical HLA-A*3001 binding assay, and a large panel of nonamer peptides and peptide libraries, we here demonstrate that the specificity of HLA-A*3001 most closely resembles that of the HLA-A3 supertype. We discuss approaches to supertype assignment and underscore the importance of experimental verification."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00251-008-0317-z"xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Buus S."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Roder G."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Nielsen M."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Lundegaard C."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Lund O."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Harndahl M."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Lamberth K."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/author | "Schafer-Nielsen C."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/name | "Immunogenetics"xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/pages | "633-643"xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/title | "The peptide-binding specificity of HLA-A*3001 demonstrates membership of the HLA-A3 supertype."xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://purl.uniprot.org/core/volume | "60"xsd:string |
| http://purl.uniprot.org/citations/18769915 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18769915 |
| http://purl.uniprot.org/citations/18769915 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A0G2R0N3-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A0G2R0N4-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A0G2R0N5-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A076JXB7-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |
| http://purl.uniprot.org/uniprot/#_A0A076L0P9-mappedCitation-18769915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18769915 |