| http://purl.uniprot.org/citations/18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18788942 | http://www.w3.org/2000/01/rdf-schema#comment | "Granzyme (grz) AB(-/-) H2(b) mice generate numerically normal cytotoxic T lymphocyte (CTL) responses to the prominent influenza A virus D(b) NP(366) and D(b) PA(224) epitopes and terminate the infectious process in the pneumonic lung with the same kinetics as the WT controls. Though grz B protein expression is fully compromised, there is only a partial effect on the level of CTL activity measured in a classical, short-term (51)Cr release assay. Single-cell polymerase chain reaction (PCR) analysis of both highly activated effector and "resting" memory CD8(+) T cells from influenza A virus-infected grzAB(-/-) mice showed a high prevalence of grzK mRNA(+) expression in tetramer (tet)(+) CTLs as was found in WT mice. However, a marked reduction in cytotoxicity present in the primary splenic CTLs of grzAB(-/-) mice correlated with decreased grzK expression, as measured by real-time PCR. This suggests that grzK plays an important role in CD8(+) T-cell cytotoxicity both in the presence and absence of grzA and B."xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.org/dc/terms/identifier | "doi:10.1089/vim.2008.0036"xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/author | "Turner S.J."xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/author | "Doherty P.C."xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/author | "Trapani J.A."xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/author | "Jenkins M.R."xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/name | "Viral Immunol"xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/pages | "341-346"xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/title | "Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB-/- mice."xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/18788942 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18788942 |
| http://purl.uniprot.org/citations/18788942 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18788942 |
| http://purl.uniprot.org/uniprot/#_P11032-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_A4FUV8-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_P04187-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_Q3TZH4-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_O35205-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_Q3TIP3-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_Q3UK79-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_Q4FJY0-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_Q3U0N0-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/#_Q9R0K0-mappedCitation-18788942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18788942 |
| http://purl.uniprot.org/uniprot/A4FUV8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18788942 |