http://purl.uniprot.org/citations/18792955 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18792955 | http://www.w3.org/2000/01/rdf-schema#comment | "N-RAP alternative splicing and protein localization were studied in developing skeletal muscle tissue from pre- and postnatal mice and in fusing primary myotubes in culture. Messages encoding N-RAP-s and N-RAP-c, the predominant isoforms of N-RAP detected in adult skeletal muscle and heart, respectively, were present in a 5:1 ratio in skeletal muscle isolated from E16.5 embryos. N-RAP-s mRNA levels increased three-fold over the first 3 weeks of postnatal development, while N-RAP-c mRNA levels remained low. N-RAP alternative splicing during myotube differentiation in culture was similar to the pattern observed in embryonic and neonatal muscle, with N-RAP-s expression increasing and N-RAP-c mRNA levels remaining low. In both developing skeletal muscle and cultured myotubes, N-RAP protein was primarily associated with developing myofibrillar structures containing alpha-actinin, but was not present in mature myofibrils. The results establish that N-RAP-s is the predominant spliced form of N-RAP present throughout skeletal muscle development."xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.org/dc/terms/identifier | "doi:10.1002/cm.20317"xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/author | "Lu S."xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/author | "Horowits R."xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/author | "Borst D.E."xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/name | "Cell Motil Cytoskeleton"xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/pages | "945-954"xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/title | "Expression and alternative splicing of N-RAP during mouse skeletal muscle development."xsd:string |
http://purl.uniprot.org/citations/18792955 | http://purl.uniprot.org/core/volume | "65"xsd:string |
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