http://purl.uniprot.org/citations/18794057 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18794057 | http://www.w3.org/2000/01/rdf-schema#comment | "We retrospectively studied the immunophenotype by flow cytometry of 20 anaplastic large cell lymphomas (ALCLs) (9 anaplastic lymphoma kinase [ALK]+ and 11 ALK-) with a particular emphasis on the aberrant expression of the myeloid associated antigens CD13 and/or CD33. All ALCLs expressed CD45, HLA-DR, and CD30. Most (8/9) ALK+ ALCLs expressed at least 1 surface T-cell antigen (CD4, 6/9 [67%]; CD7, 6/9 [67%]; CD2, 5/9 [56%]; CD5, 2/9 [22%]; CD8, 2/9 [22%]; CD3, 1/9 [11%]). All ALK-ALCLs expressed at least 1 surface T-cell antigen (CD3, 7/11 [64%]; CD4, 6/11 [55%]; CD2, 6/11 [55%]; CD7, 2/11 [18%]; CD5, 1/11 [9%]; CD8, 1/11 [9%]). CD13 and/or CD33 were expressed in all (9/9) ALK+ ALCLs compared with 1 of 11 ALK-ALCLs (9%) (P < .0001). Surface CD3 was more likely expressed in ALK-ALCLs (7/11) compared with ALK+ ALCLs (1/9) (P .03). The myeloid-associated antigens CD13 and/or CD33 are sensitive but not entirely specific markers of ALK+ ALCLs and should not be misinterpreted as indicating myeloid sarcoma."xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.org/dc/terms/identifier | "doi:10.1309/pln1na4qb2pc1cmq"xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/author | "Allan R.W."xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/author | "Bovio I.M."xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/name | "Am J Clin Pathol"xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/pages | "628-634"xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/title | "The expression of myeloid antigens CD13 and/or CD33 is a marker of ALK+ anaplastic large cell lymphomas."xsd:string |
http://purl.uniprot.org/citations/18794057 | http://purl.uniprot.org/core/volume | "130"xsd:string |
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