| http://purl.uniprot.org/citations/18822333 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18822333 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18822333 | http://www.w3.org/2000/01/rdf-schema#comment | "In this study we have evaluated the vaccine potential of a Mycobacterium tuberculosis antigen of the PPE protein family, namely PPE44 (Rv2770c). PPE44-specific immune responses could be detected in mice acutely, chronically and latently infected with M. tuberculosis. Vaccination of mice with a plasmid DNA vaccine coding for PPE44 or recombinant PPE44 protein formulated in adjuvant generated strong cellular and humoral immune responses; immunodominant T cell epitopes were identified. Most importantly, vaccination of mice with both subunit vaccines followed by an intratracheal challenge with M. tuberculosis resulted in a protective efficacy comparable to the one afforded by BCG. Taken together these results indicate that PPE44 of M. tuberculosis is a protective antigen that could be included in novel subunit TB vaccines and that warrants further analysis."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.vaccine.2008.09.025"xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.vaccine.2008.09.025"xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Huygen K."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Huygen K."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Korf H."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Korf H."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Romano M."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Romano M."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Rindi L."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Rindi L."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Bonanni D."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Bonanni D."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Garzelli C."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Garzelli C."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Adnet P.-Y."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Adnet P.-Y."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Jurion F."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/author | "Jurion F."xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/name | "Vaccine"xsd:string |
| http://purl.uniprot.org/citations/18822333 | http://purl.uniprot.org/core/name | "Vaccine"xsd:string |