| http://purl.uniprot.org/citations/18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18842901 | http://www.w3.org/2000/01/rdf-schema#comment | "Vertebrate brain hosts a diverse collection of microRNAs, but little is known about their functions in vivo. Here we propose that mouse microRNA-9 (miR-9) targets Foxg1 mRNAs for proper generation of Cajal-Retzius cells in the medial pallium. miR-9 expression is mediolaterally graded, being most intense in the cortical hem; it contrasts with the Foxg1 expression in a reciprocal gradient. The 3' untranslated regions of tetrapod, but not of teleost, Foxg1 mRNAs conserve miR-9 target sequences and are regulated by miR-9. Gain- and loss-of-function analyses of miR-9 showed that miR-9 negatively regulates endogenous Foxg1 protein level. Moreover, miR-9 overexpression in developing telencephalon at E11.5 by electroporation resulted in ectopic Reelin-positive cells over the cortex beyond the marginal zone. In addition, inhibition of endogenous miR-9 function by antisense oligonucleotides caused the regression of Wnt3a-positive cortical hem and reduction of reelin-, p73-, and NeuroD1-positive cells."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.3219-08.2008"xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/author | "Aizawa S."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/author | "Shibata M."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/author | "Nakao H."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/author | "Ohmura T."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/author | "Kurokawa D."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/name | "J Neurosci"xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/pages | "10415-10421"xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/title | "MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium."xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/18842901 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18842901 |
| http://purl.uniprot.org/citations/18842901 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18842901 |
| http://purl.uniprot.org/uniprot/Q60987#attribution-E5039D7FA3B98B5F39645ACE00DE1E6E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/#_P27467-mappedCitation-18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/#_P07309-mappedCitation-18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/#_Q3V1Q8-mappedCitation-18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/#_Q5M9K1-mappedCitation-18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/#_Q60987-mappedCitation-18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/#_Q9D6A4-mappedCitation-18842901 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/Q9D6A4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/P07309 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18842901 |
| http://purl.uniprot.org/uniprot/Q5M9K1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/18842901 |