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http://purl.uniprot.org/citations/18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18924241http://www.w3.org/2000/01/rdf-schema#comment"Lysophospholipids (LPs) such as lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are known to mediate various biological responses, including cell proliferation, migration, and differentiation. To better understand the role of these lipids in mammalian early development, we applied whole-mount in situ hybridization techniques to E8.5 to E12.5 mouse embryos. We determined the expression patterns of the following LP receptor genes, which belong to the G protein-coupled receptor (GPCR) family: EDG1 to EDG8 (S1P1 to S1P5 and LPA1 to LPA3), LPA4 (GPR23/P2Y9), and LPA5 (GPR92). We found that the S1P/LPA receptor genes exhibit overlapping expression patterns in a variety of organ primordia, including the developing brain and cardiovascular system, presomitic mesoderm and somites, branchial arches, and limb buds. These results suggest that multiple receptor systems for LPA/S1P lysophospholipids may be functioning during organogenesis."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.org/dc/terms/identifier"doi:10.1002/dvdy.21736"xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Arai H."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Aoki J."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Matsuda H."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Tanaka M."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Hamada A."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Noji S."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Ohuchi H."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/author"Takagi A."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/name"Dev Dyn"xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/pages"3280-3294"xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/title"Expression patterns of the lysophospholipid receptor genes during mouse early development."xsd:string
http://purl.uniprot.org/citations/18924241http://purl.uniprot.org/core/volume"237"xsd:string
http://purl.uniprot.org/citations/18924241http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18924241
http://purl.uniprot.org/citations/18924241http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/18924241
http://purl.uniprot.org/uniprot/#_A0A1L1ST05-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241
http://purl.uniprot.org/uniprot/#_P61793-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241
http://purl.uniprot.org/uniprot/#_A0A2I3BS26-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241
http://purl.uniprot.org/uniprot/#_A0A571BEW5-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241
http://purl.uniprot.org/uniprot/#_A2AMI9-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241
http://purl.uniprot.org/uniprot/#_A2AMJ0-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241
http://purl.uniprot.org/uniprot/#_A2AMJ1-mappedCitation-18924241http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/18924241