http://purl.uniprot.org/citations/18950027 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18950027 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo investigate the expression and clinical significance of cyclin H and cyclin-dependent kinase 7 (CDK7) in human hemangiomas.MethodsImmunohistochemistry technique was used to measure the expression of cyclin H and CDK7 proteins in proliferative, involuting hemangiomas and normal skin tissues. Immunohistochemical technique for factor VIII-related antigen was used to prove that the cells which expressed cyclin H and CDK7 were endothelial cells. Average optical density and positive area of the expression of cyclin H and CDK7 proteins in proliferative, involuting hemangiomas and normal skin tissues were measured by image analysis (HPIAS-1000).ResultsThe expression of cyclin H and CDK7 protein in proliferating hemangiomas was significantly higher than that in involuting hemangiomas and normal skin tissues (P < 0.01). But no significant difference was found in the expression of cyclin H and CDK7 protein between involuting hemangiomas and normal skin tissues (P > 0.05).Conclusionscyclin H and CDK7 may play an important role in the generation and development of human hemangiomas."xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/author | "Liu J."xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/author | "Zhang D.L."xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/author | "Shan S.G."xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/name | "Zhonghua Zheng Xing Wai Ke Za Zhi"xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/pages | "300-302"xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/title | "[Expression and clinical significance of cyclin H and CDK7 in human hemangiomas]."xsd:string |
http://purl.uniprot.org/citations/18950027 | http://purl.uniprot.org/core/volume | "24"xsd:string |
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