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http://purl.uniprot.org/citations/1899836http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1899836http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1899836http://www.w3.org/2000/01/rdf-schema#comment"The zinc-binding properties of an endogenous protein inhibitor of protein kinase C was studied. Equilibrium gel penetration revealed that 1 mol of this protein binds 0.97 mol of zinc with a dissociation constant of 4.3 microM. The site of zinc-binding, MVVNEGSDGGQSVYHVHLHVLGGR, was identified by a multi-step process consisting of tryptic digestion, fragment isolation, transfer to nitrocellulose, and hybridization with 65ZnCl2. Binding of 65ZnCl2 to selected synthetic fragments further localized the site of interaction to the sequence QSVYHVHLHVL. This region contains 3 closely positioned histidine residues and represents a novel zinc-binding site."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(91)80238-x"xsd:string
http://purl.uniprot.org/citations/1899836http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(91)80238-x"xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/author"Pearson J.D."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/author"Pearson J.D."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/author"Walsh M.P."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/author"Walsh M.P."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/author"Mozier N.M."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/author"Mozier N.M."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/pages"14-18"xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/pages"14-18"xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/title"Characterization of a novel zinc binding site of protein kinase C inhibitor-1."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/title"Characterization of a novel zinc binding site of protein kinase C inhibitor-1."xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/volume"279"xsd:string
http://purl.uniprot.org/citations/1899836http://purl.uniprot.org/core/volume"279"xsd:string
http://purl.uniprot.org/citations/1899836http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1899836
http://purl.uniprot.org/citations/1899836http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1899836
http://purl.uniprot.org/citations/1899836http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1899836
http://purl.uniprot.org/citations/1899836http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1899836