RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/19000842http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19000842http://www.w3.org/2000/01/rdf-schema#comment"Kidney development is based on differential cell-type-specific expression of a vast number of genes. While multiple critical genes and pathways have been elucidated, a genome-wide analysis of gene expression within individual cellular and anatomic structures is lacking. Accomplishing this could provide significant new insights into fundamental developmental mechanisms such as mesenchymal-epithelial transition, inductive signaling, branching morphogenesis, and segmentation. We describe here a comprehensive gene expression atlas of the developing mouse kidney based on the isolation of each major compartment by either laser capture microdissection or fluorescence-activated cell sorting, followed by microarray profiling. The resulting data agree with known expression patterns and additional in situ hybridizations. This kidney atlas allows a comprehensive analysis of the progression of gene expression states during nephrogenesis, as well as discovery of potential growth factor-receptor interactions. In addition, the results provide deeper insight into the genetic regulatory mechanisms of kidney development."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2008.09.007"xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Yu J."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Grimmond S."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Aronow B.J."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"McMahon A.P."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Little M.H."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Brunskill E.W."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Georgas K."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Potter S.S."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Valerius M.T."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Jegga A.G."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Rumballe B."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Patterson L.T."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Aronow J."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/author"Kaimal V."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/name"Dev Cell"xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/pages"781-791"xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/title"Atlas of gene expression in the developing kidney at microanatomic resolution."xsd:string
http://purl.uniprot.org/citations/19000842http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/19000842http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19000842
http://purl.uniprot.org/citations/19000842http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19000842
http://purl.uniprot.org/uniprot/#_A0A087WQM9-mappedCitation-19000842http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19000842