| http://purl.uniprot.org/citations/1900243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1900243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1900243 | http://www.w3.org/2000/01/rdf-schema#comment | "Ordered rearrangement of immunoglobulin genes (heavy chain then kappa and eventually lambda genes) is observed during B lymphocyte ontogeny. Unexpectedly, we found that human mature B cells producing kappa chains and having germ-line lambda genes contain lambda mRNA consisting of an invariant 5' region (herein termed X) and of one of the classical C lambda exons. The X region of these transcripts originates from a unique exon located 5 kb upstream of the J-C lambda 1 gene segment. X-C lambda mRNA expression occurs without somatic DNA rearrangement. The use of the X DNA fragment as a probe allows definition of a family of human genes that comprises at least four members and includes the first exon of the lambda 14.1 gene. The latter is selectively transcribed in pre-B lymphocytes and directs the synthesis of a lambda-like chain. In contrast, the X-C lambda transcripts do not appear to encode a C lambda-related polypeptide in mature B cells. Thus, despite a 73% homology extending far beyond the exon sequences, the X and lambda 14.1 genes are expressed at different stages of B cell development and might serve different functions."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830210237"xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830210237"xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/author | "Guglielmi P."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/author | "Guglielmi P."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/author | "Davi F."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/author | "Davi F."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/pages | "501-508"xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/pages | "501-508"xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/title | "Expression of a novel type of immunoglobulin C lambda transcripts in human mature B lymphocytes producing kappa light chains."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/title | "Expression of a novel type of immunoglobulin C lambda transcripts in human mature B lymphocytes producing kappa light chains."xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://purl.uniprot.org/core/volume | "21"xsd:string |
| http://purl.uniprot.org/citations/1900243 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1900243 |
| http://purl.uniprot.org/citations/1900243 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1900243 |
| http://purl.uniprot.org/citations/1900243 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1900243 |
| http://purl.uniprot.org/citations/1900243 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1900243 |
| http://purl.uniprot.org/uniprot/B9A064 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1900243 |
| http://purl.uniprot.org/uniprot/B9A064#attribution-4FE5FAB42BC5780DEC97A374A74752C1 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1900243 |