http://purl.uniprot.org/citations/19005011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19005011 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19005011 | http://www.w3.org/2000/01/rdf-schema#comment | "Myosin 1e (Myo1e) is one of two Src homology 3 domain-containing "long-tailed" type I myosins in vertebrates, whose functions in health and disease are incompletely understood. Here, we demonstrate that Myo1e localizes to podocytes in the kidney. We generated Myo1e-knockout mice and found that they exhibit proteinuria, signs of chronic renal injury, and kidney inflammation. At the ultrastructural level, renal tissue from Myo1e-null mice demonstrates changes characteristic of glomerular disease, including a thickened and disorganized glomerular basement membrane and flattened podocyte foot processes. These observations suggest that Myo1e plays an important role in podocyte function and normal glomerular filtration."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.org/dc/terms/identifier | "doi:10.1681/asn.2007111172"xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.org/dc/terms/identifier | "doi:10.1681/asn.2007111172"xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Krendel M."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Krendel M."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Wang T."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Wang T."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Flavell R.A."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Flavell R.A."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Mooseker M.S."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Mooseker M.S."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Kashgarian M."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Kashgarian M."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Kim S.V."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Kim S.V."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Willinger T."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/author | "Willinger T."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/name | "J. Am. Soc. Nephrol."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/name | "J. Am. Soc. Nephrol."xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/pages | "86-94"xsd:string |
http://purl.uniprot.org/citations/19005011 | http://purl.uniprot.org/core/pages | "86-94"xsd:string |