| http://purl.uniprot.org/citations/19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19013177 | http://www.w3.org/2000/01/rdf-schema#comment | "When heat shock prematurely dissociates a translating bacterial ribosome, its 50S subunit is prevented from reinitiating protein synthesis by tRNA covalently linked to the unfinished protein chain that remains threaded through the exit tunnel. Hsp15, a highly upregulated bacterial heat shock protein, reactivates such dead-end complexes. Here, we show with cryo-electron microscopy reconstructions and functional assays that Hsp15 translocates the tRNA moiety from the A site to the P site of stalled 50S subunits. By stabilizing the tRNA in the P site, Hsp15 indirectly frees up the A site, allowing a release factor to land there and cleave off the tRNA. Such a release factor must be stop codon independent, suggesting a possible role for a poorly characterized class of putative release factors that are upregulated by cellular stress, lack a codon recognition domain and are conserved in eukaryotes."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jmb.2008.10.079"xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Ban N."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Jiang L."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Korber P."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Plaisier J.R."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Abrahams J.P."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Koning R.I."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Schaffitzel C."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "de Geus D.C."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/author | "Bingel-Erlenmeyer R."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/name | "J Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/pages | "1357-1367"xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/title | "Recycling of aborted ribosomal 50S subunit-nascent chain-tRNA complexes by the heat shock protein Hsp15."xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://purl.uniprot.org/core/volume | "386"xsd:string |
| http://purl.uniprot.org/citations/19013177 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19013177 |
| http://purl.uniprot.org/citations/19013177 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19013177 |
| http://purl.uniprot.org/uniprot/#_P0ADZ0-mappedCitation-19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19013177 |
| http://purl.uniprot.org/uniprot/#_P0AG44-mappedCitation-19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19013177 |
| http://purl.uniprot.org/uniprot/#_P0AG48-mappedCitation-19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19013177 |
| http://purl.uniprot.org/uniprot/#_P0AG51-mappedCitation-19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19013177 |
| http://purl.uniprot.org/uniprot/#_P0AG55-mappedCitation-19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19013177 |
| http://purl.uniprot.org/uniprot/#_P0C018-mappedCitation-19013177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19013177 |