http://purl.uniprot.org/citations/19013515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19013515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19013515 | http://www.w3.org/2000/01/rdf-schema#comment | "In the nervous system the Liprin-alpha protein family plays an important role in the regulation of dendrite development, the targeting of photoreceptor axons, and the formation and structure of synapses. To gain a better understanding of Liprin-alpha regulation we have comparatively analyzed the genomic organization of the human and mouse Liprin-alpha genes, characterized the alternative exon use in human and mouse, and studied their expression in adult rodent tissues and brain regions. Our results show that Liprins-alpha1-4 share multiple properties in their genomic structure, exhibit an identical modular organization, and are highly conserved within certain structural domains, indicating strong evolutionary cohesion. We demonstrate that all Liprin-alpha genes are subject to alternative splicing, which is regulated in a developmental manner. Interestingly, regulation via alternative splicing is not conserved between isoforms and across species and represents a post-transcriptional mechanism to independently diversify the properties of the individual isoforms."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ygeno.2008.10.007"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ygeno.2008.10.007"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/author | "Schoch S."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/author | "Schoch S."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/author | "Zurner M."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/author | "Zurner M."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/pages | "243-253"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/pages | "243-253"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/title | "The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/title | "The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing."xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/volume | "93"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://purl.uniprot.org/core/volume | "93"xsd:string |
http://purl.uniprot.org/citations/19013515 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19013515 |
http://purl.uniprot.org/citations/19013515 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19013515 |
http://purl.uniprot.org/citations/19013515 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19013515 |
http://purl.uniprot.org/citations/19013515 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19013515 |
http://purl.uniprot.org/uniprot/B8QI34 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/19013515 |
http://purl.uniprot.org/uniprot/P60469 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/19013515 |