http://purl.uniprot.org/citations/19018105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19018105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19018105 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/19018105 | http://www.w3.org/2000/01/rdf-schema#comment | "The hyperthermophilic archaeon Sulfolobus solfataricus grows optimally above 353 K and utilizes an unusual promiscuous nonphosphorylative Entner-Doudoroff pathway to metabolize both glucose and galactose. It has been proposed that a part-phosphorylative Entner-Doudoroff pathway occurs in parallel in S. solfataricus, in which the 2-keto-3-deoxygluconate kinase (KDGK) is promiscuous for both glucose and galactose metabolism. Recombinant S. solfataricus KDGK protein was expressed in Escherichia coli, purified and crystallized in 0.1 M sodium acetate pH 4.1 and 1.4 M NaCl. The crystal structure of apo S. solfataricus KDGK was solved by molecular replacement to a resolution of 2.0 A and a ternary complex with 2-keto-3-deoxygluconate (KDGlu) and an ATP analogue was resolved at 2.1 A. The complex suggests that the structural basis for the enzyme's ability to phosphorylate KDGlu and 2-keto-3-deoxygalactonate (KDGal) is derived from a subtle repositioning of residues that are conserved in homologous nonpromiscuous kinases."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/name | "Acta Crystallogr. D"xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/name | "Acta Crystallogr. D"xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.org/dc/terms/identifier | "doi:10.1107/s0907444908036111"xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.org/dc/terms/identifier | "doi:10.1107/s0907444908036111"xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.org/dc/terms/identifier | "doi:10.1107/s0907444908036111"xsd:string |
http://purl.uniprot.org/citations/19018105 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19018105 |
http://purl.uniprot.org/citations/19018105 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19018105 |
http://purl.uniprot.org/citations/19018105 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19018105 |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Kerou M."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Kerou M."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Danson M.J."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Danson M.J."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Potter J.A."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Potter J.A."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Taylor G.L."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Taylor G.L."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Hough D.W."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Hough D.W."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Bull S.D."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Bull S.D."xsd:string |
http://purl.uniprot.org/citations/19018105 | http://purl.uniprot.org/core/author | "Lamble H.J."xsd:string |