| http://purl.uniprot.org/citations/19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19039313 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate the associations of uncoupling protein (UCP)2 and UCP3 gene variants with overweight and related traits, we genotyped UCP2-866G>A, UCP2Ala55Val, and UCP3-55C>T in 737 Korean children and 732 adults and collected data regarding anthropometric status and blood biochemistry. Information concerning the children's lifestyles and dietary habits was collected. The UCP2-866G>A and UCP3-55C>T gene variants showed significant associations with BMI level, waist circumference, and body weight in the children but not in the adults. Compared with -866GG carriers, the -866GA and AA carriers showed a strong decreasing trend in the risk for overweight (odds ratio (OR), 0.67; 95% confidence interval (CI), 0.45-1.01; P = 0.053). In comparison with UCP3-55CC carriers, children carrying -55CT and TT showed a significant reduction in the risk of overweight (OR, 0.67; 95% CI, 0.46-0.98; P = 0.039). There was also evidence of interactions between the effects of the combined UCP2-UCP3 genotype and obesity-related metabolic traits. The greatest protective effect against overweight was seen in those with the combined genotype non-UCP2-866GG and non-UCP3-55CC, as compared with those carrying both UCP2-866GG and UCP3-55CC (OR,0.60; 95% CI, 0.38-0.95; P = 0.030). In the subgroup with a low level of physical activity, UCP3-55CC carriers had higher BMI values than UCP3-55T carriers (16.6 +/- 2.3 kg/m(2) vs. 16.1 +/-1.9 kg/m(2), P = 0.016). Low physical activity may aggravate the susceptibility to overweight in UCP2-866GG and UCP3-55CC carriers."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.org/dc/terms/identifier | "doi:10.1038/oby.2008.531"xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Song J."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Lee H.J."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Kim J.R."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Kim I.K."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Kang J.H."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Jun H.S."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Shin H.D."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/author | "Lee H.J.'"xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/name | "Obesity (Silver Spring)"xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/pages | "355-362"xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/title | "Effects of UCP2 and UCP3 variants on the manifestation of overweight in Korean children."xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/19039313 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19039313 |
| http://purl.uniprot.org/citations/19039313 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19039313 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z4G2-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z4G5-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |
| http://purl.uniprot.org/uniprot/#_A8K3L5-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |
| http://purl.uniprot.org/uniprot/#_A8K774-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |
| http://purl.uniprot.org/uniprot/#_B3KS33-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |
| http://purl.uniprot.org/uniprot/#_P55851-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |
| http://purl.uniprot.org/uniprot/#_P55916-mappedCitation-19039313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19039313 |