http://purl.uniprot.org/citations/19052383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19052383 | http://www.w3.org/2000/01/rdf-schema#comment | "Sox17 is a member of the SRY-related high-mobility group (HMG) of transcription factors that have been shown to direct endodermal differentiation in early mammalian development. The LAMA1 gene encoding the alpha-chain of laminin-1 has been reported to be directly bound and regulated by Sox17. This paper describes the details of initial crystallization attempts with the HMG domain of mouse Sox17 (mSox17-HMG) with a 16-mer DNA element derived from the LAMA1 enhancer and optimization strategies to obtain a better diffracting crystal. The best diffracting crystal was obtained in a condition containing 0.1 M Tris-HCl pH 7.4, 0.2 M MgCl(2), 30% PEG 3350 using the hanging-drop vapour-diffusion method. A highly redundant in-house data set was collected to 2.75 A resolution with 99% completeness. The presence of the mSox17-HMG-DNA complex within the crystals was confirmed and Matthews analysis indicated the presence of one complex per asymmetric unit."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.org/dc/terms/identifier | "doi:10.1107/s1744309108038724"xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Cheng J."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Kolatkar P.R."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Palasingam P."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Ng C.K."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Jauch R."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Baburajendran N."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/author | "Venkatachalam R."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/name | "Acta Crystallogr Sect F Struct Biol Cryst Commun"xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/pages | "1184-1187"xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/title | "Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA."xsd:string |
http://purl.uniprot.org/citations/19052383 | http://purl.uniprot.org/core/volume | "64"xsd:string |
http://purl.uniprot.org/citations/19052383 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19052383 |
http://purl.uniprot.org/citations/19052383 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19052383 |
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http://purl.uniprot.org/uniprot/#_Q61473-mappedCitation-19052383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19052383 |
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http://purl.uniprot.org/uniprot/Q61473 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19052383 |
http://purl.uniprot.org/uniprot/Q6P9T1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19052383 |
http://purl.uniprot.org/uniprot/A0A0A6YXS3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19052383 |