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http://purl.uniprot.org/citations/19052383http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19052383http://www.w3.org/2000/01/rdf-schema#comment"Sox17 is a member of the SRY-related high-mobility group (HMG) of transcription factors that have been shown to direct endodermal differentiation in early mammalian development. The LAMA1 gene encoding the alpha-chain of laminin-1 has been reported to be directly bound and regulated by Sox17. This paper describes the details of initial crystallization attempts with the HMG domain of mouse Sox17 (mSox17-HMG) with a 16-mer DNA element derived from the LAMA1 enhancer and optimization strategies to obtain a better diffracting crystal. The best diffracting crystal was obtained in a condition containing 0.1 M Tris-HCl pH 7.4, 0.2 M MgCl(2), 30% PEG 3350 using the hanging-drop vapour-diffusion method. A highly redundant in-house data set was collected to 2.75 A resolution with 99% completeness. The presence of the mSox17-HMG-DNA complex within the crystals was confirmed and Matthews analysis indicated the presence of one complex per asymmetric unit."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.org/dc/terms/identifier"doi:10.1107/s1744309108038724"xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Cheng J."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Kolatkar P.R."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Palasingam P."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Ng C.K."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Jauch R."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Baburajendran N."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/author"Venkatachalam R."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/name"Acta Crystallogr Sect F Struct Biol Cryst Commun"xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/pages"1184-1187"xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/title"Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA."xsd:string
http://purl.uniprot.org/citations/19052383http://purl.uniprot.org/core/volume"64"xsd:string
http://purl.uniprot.org/citations/19052383http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19052383
http://purl.uniprot.org/citations/19052383http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19052383
http://purl.uniprot.org/uniprot/#_A0A0A6YXS3-mappedCitation-19052383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19052383
http://purl.uniprot.org/uniprot/#_Q61473-mappedCitation-19052383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19052383
http://purl.uniprot.org/uniprot/#_Q6P9T1-mappedCitation-19052383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19052383
http://purl.uniprot.org/uniprot/Q61473http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19052383
http://purl.uniprot.org/uniprot/Q6P9T1http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19052383
http://purl.uniprot.org/uniprot/A0A0A6YXS3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19052383