| http://purl.uniprot.org/citations/19071173 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19071173 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19071173 | http://www.w3.org/2000/01/rdf-schema#comment | "The degradation of intracytosolic proteins has been well described. However, the degradation pathway and physiological functions of the DNA-Bound peptides, which are free of degradation by peptidase of the post-ubiquitin-proteasome pathway, are still unclear. In this study, the DNA-Bound peptides were isolated from barley germ and two main fractions of about 25 different peptides were obtained. The DNA-Bound peptides were found to inhibit the proliferation of HeLa cells in a series of experiments. The DNA-Bound peptides also significantly inhibited in vitro and in vivo DNA transcription activity by regulating the expression and the corresponding functions of CDK7. Furthermore, signaling issues involving NFkappaB and ERK1/2 were observed. Such data suggests that DNA transcription could be inhibited by the DNA-Bound peptides via the CDK7 pathway. Thus we concluded that some of the post-proteasomal peptides were involved in the regulation of eukaryotic mRNA transcription."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.peptides.2008.11.008"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.peptides.2008.11.008"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Dong Z."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Dong Z."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Qin Y."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Qin Y."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Lv X."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Lv X."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Lv F."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/author | "Lv F."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/name | "Peptides"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/name | "Peptides"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/pages | "681-688"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/pages | "681-688"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/title | "DNA-Bound peptides control the mRNA transcription through CDK7."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/title | "DNA-Bound peptides control the mRNA transcription through CDK7."xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/19071173 | http://purl.uniprot.org/core/volume | "30"xsd:string |