| http://purl.uniprot.org/citations/19073903 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19073903 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19073903 | http://www.w3.org/2000/01/rdf-schema#comment | "Stanniocalcin (STC) formerly called hypocalcin or teleocalcin, is a 50-kDa disulfide-linked homodimeric glycoprotein that was originally identified in fish and secreted from the corpuscles of Stannius (CS). One of the main functions of STC-1 is Ca(2+) uptake inhibition; however, the mechanisms remain unknown. In the present study, we provide molecular evidence to elucidate how zebrafish STC-1 regulates Ca(2+) uptake in zebrafish embryos. In a wide variety of tissues including the kidney, brain, gill, muscle, and skin, zstc-1 was expressed. Incubating zebrafish embryos in low-Ca(2+) (0.02 mM) freshwater stimulated whole body Ca(2+) influx and zebrafish epithelial Ca(2+) channel (zECaC) mRNA expression, while downregulated zstc-1 expression. A morpholino microinjection approach was used to knockdown the zSTC-1 protein, and the results showed that the Ca(2+) content, Ca(2+) influx, and zECaC mRNA expression all increased in morphants. These data suggest that zSTC-1 negatively regulates ECaC gene expression to reduce Ca(2+) uptake in zebrafish embryos."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajpregu.90742.2008"xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Huang C.J."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Huang C.J."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Kaneko T."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Kaneko T."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Hsiao C.D."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Hsiao C.D."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Hwang P.P."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Hwang P.P."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Chou M.Y."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Chou M.Y."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Tseng Y.C."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Tseng Y.C."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Tseng D.Y."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/author | "Tseng D.Y."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/name | "Am. J. Physiol. Regul. Integr. Comp. Physiol."xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/name | "Am J Physiol Regul Integr Comp Physiol"xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/pages | "R549-R557"xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/pages | "R549-57"xsd:string |
| http://purl.uniprot.org/citations/19073903 | http://purl.uniprot.org/core/title | "Effects of stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo."xsd:string |