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http://purl.uniprot.org/citations/19074389http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19074389http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19074389http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19074389http://www.w3.org/2000/01/rdf-schema#comment"We isolated the methicillin-resistant Macrococcus caseolyticus strain JCSC5402 from animal meat in a supermarket and determined its whole-genome nucleotide sequence. This is the first report on the genome analysis of a macrococcal species that is evolutionarily closely related to the human pathogens Staphylococcus aureus and Bacillus anthracis. The essential biological pathways of M. caseolyticus are similar to those of staphylococci. However, the species has a small chromosome (2.1 MB) and lacks many sugar and amino acid metabolism pathways and a plethora of virulence genes that are present in S. aureus. On the other hand, M. caseolyticus possesses a series of oxidative phosphorylation machineries that are closely related to those in the family Bacillaceae. We also discovered a probable primordial form of a Macrococcus methicillin resistance gene complex, mecIRAm, on one of the eight plasmids harbored by the M. caseolyticus strain. This is the first finding of a plasmid-encoding methicillin resistance gene. Macrococcus is considered to reflect the genome of ancestral bacteria before the speciation of staphylococcal species and may be closely associated with the origin of the methicillin resistance gene complex of the notorious human pathogen methicillin-resistant S. aureus."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.org/dc/terms/identifier"doi:10.1128/jb.01058-08"xsd:string
http://purl.uniprot.org/citations/19074389http://purl.org/dc/terms/identifier"doi:10.1128/jb.01058-08"xsd:string
http://purl.uniprot.org/citations/19074389http://purl.org/dc/terms/identifier"doi:10.1128/jb.01058-08"xsd:string
http://purl.uniprot.org/citations/19074389http://purl.org/dc/terms/identifier"doi:10.1128/JB.01058-08"xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Uchiyama I."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Uchiyama I."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Uchiyama I."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Baba T."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Baba T."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Baba T."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Hiramatsu K."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Hiramatsu K."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Hiramatsu K."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Ito T."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Ito T."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Ito T."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Kuwahara-Arai K."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Kuwahara-Arai K."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Kuwahara-Arai K."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Takeuchi F."xsd:string
http://purl.uniprot.org/citations/19074389http://purl.uniprot.org/core/author"Takeuchi F."xsd:string