| http://purl.uniprot.org/citations/19087983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19087983 | http://www.w3.org/2000/01/rdf-schema#comment | "Recent findings implicate protein kinase C in regulation of contraction of uterine muscle (myometrium). However, the role of protein kinase C isoforms in myometrial contraction remains uncertain. Therefore, this study examined protein kinase Calpha's role in regulation of contraction and intracellular calcium concentration ([Ca2+](I)) of myometrium from term pregnant women. The authors demonstrated that protein kinase Calpha inhibitor Go6976 decreased the amplitude of potassium chloride-induced myometrial contractions in a time-dependent manner. The treatment of the myometrial strips with protein kinase Calpha-specific antisense oligodeoxynucleotides decreased the potassium chloride-induced contraction and [Ca2+](I) response to 39.3% + 6.8% and 50.0% + 3.3%, respectively, compared to control. The sense oligonucleotides treatment did not significantly change the potassium chloride responses (89.8% + 6.8% and 93.9% + 4.5% of the control for the contraction and [Ca2+](I), respectively). These data, coupled with the observation that protein kinase Calpha levels are elevated in the pregnant myometrium, suggest the involvement of protein kinase Calpha in regulation of human uterine contraction."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.org/dc/terms/identifier | "doi:10.1177/1933719108324892"xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Tang D."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Hoffman M."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Duncan R.L."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Fomin V.P."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Gunst S."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Kronbergs A."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/author | "Simirskii V."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/name | "Reprod Sci"xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/pages | "71-79"xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/title | "Role of protein kinase Calpha in regulation of [Ca2+](I) and force in human myometrium."xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/19087983 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19087983 |
| http://purl.uniprot.org/citations/19087983 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19087983 |
| http://purl.uniprot.org/uniprot/#_A0A169TED2-mappedCitation-19087983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19087983 |
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| http://purl.uniprot.org/uniprot/#_Q7Z727-mappedCitation-19087983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19087983 |
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| http://purl.uniprot.org/uniprot/#_Q2TSD3-mappedCitation-19087983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19087983 |
| http://purl.uniprot.org/uniprot/#_Q59FI5-mappedCitation-19087983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19087983 |
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