| http://purl.uniprot.org/citations/19095005 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19095005 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19095005 | http://www.w3.org/2000/01/rdf-schema#comment | "Ca(2+) mobilization from intracellular stores is mediated by Ca(2+) release channels, designated ryanodine and IP(3) receptors, and directly regulates important cellular reactions including muscle contraction, endo/exocrine secretion, and neural excitability. In order to function as an intracellular store, the endo/sarcoplasmic reticulum is equipped with cooperative Ca(2+) uptake, storage and release machineries, comprising synergic collaborations among integral-membrane, cytoplasmic and luminal proteins. Our recent studies have demonstrated that junctophilins form junctional membrane complexes between the plasma membrane and the endo/sarcoplasmic reticulum in excitable cells, and that TRIC (trimeric intracellular cation) channels act as novel monovalent cation-specific channels on intracellular membrane systems. Knockout mice have provided evidence that both junctophilins and TRIC channels support efficient ryanodine receptor-mediated Ca(2+) release in muscle cells. This review focuses on cardiac Ca(2+) release by discussing pathological defects of mutant cardiomyocytes lacking ryanodine receptors, junctophilins, or TRIC channels."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.pharmthera.2008.11.004"xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.pharmthera.2008.11.004"xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/author | "Takeshima H."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/author | "Takeshima H."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/author | "Yamazaki T."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/author | "Yamazaki T."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/author | "Yamazaki D."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/author | "Yamazaki D."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/name | "Pharmacol. Ther."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/name | "Pharmacol. Ther."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/pages | "265-272"xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/pages | "265-272"xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/title | "New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/title | "New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes."xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/volume | "121"xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://purl.uniprot.org/core/volume | "121"xsd:string |
| http://purl.uniprot.org/citations/19095005 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19095005 |
| http://purl.uniprot.org/citations/19095005 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19095005 |
| http://purl.uniprot.org/citations/19095005 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19095005 |
| http://purl.uniprot.org/citations/19095005 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19095005 |