| http://purl.uniprot.org/citations/19098279 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19098279 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice with null mutations of ciliary neurotrophic factor (Cntf) receptor alpha (Cntf-Ralpha), or cytokine-like factor 1 (Clf), one component of Cntf-II (a heterodimeric Cntf-Ralpha ligand), die as neonates from motor neuron loss affecting the facial nucleus and ventral horn of the lumbar spinal cord. Exposure to cardiotrophin-like cytokine (Clc), the other putative Cntf-II element, supports motor neuron survival in vitro and in ovo. Confirmation that Clc ablation induces an equivalent phenotype to Clf deletion would support a role for Clc in the functional Cntf-II complex. In this study, Clc knockout mice had decreased facial motility, did not suckle, died within 24 hours, and had 32% and 29% fewer motor neurons in the facial nucleus and lumbar ventral horn, respectively; thus, Clc is essential for motor neuron survival during development. The concordance of the Clc knockout phenotype with those of mice lacking Cntf-Ralpha or Clf bolsters the hypothesis that Clc participates in Cntf-II."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.org/dc/terms/identifier | "doi:10.1354/vp.08-vp-0239-b-bc"xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Sun N."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Zou X."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Foreman O."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Siu G."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Kurahara C."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Senaldi G."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Bolon B."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Duryea D."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Christiansen K.A."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "McCabe J."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Itano A.A."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/author | "Pretorius J.K."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/name | "Vet Pathol"xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/pages | "514-519"xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/title | "Neonatal death in mice lacking cardiotrophin-like cytokine is associated with multifocal neuronal hypoplasia."xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://purl.uniprot.org/core/volume | "46"xsd:string |
| http://purl.uniprot.org/citations/19098279 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19098279 |
| http://purl.uniprot.org/citations/19098279 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19098279 |
| http://purl.uniprot.org/uniprot/#_A0A494BA42-mappedCitation-19098279 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19098279 |
| http://purl.uniprot.org/uniprot/#_D6RIL9-mappedCitation-19098279 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19098279 |
| http://purl.uniprot.org/uniprot/#_P51642-mappedCitation-19098279 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19098279 |