http://purl.uniprot.org/citations/19111545 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19111545 | http://www.w3.org/2000/01/rdf-schema#comment | "Adenine nucleotide translocase (ANT) is known as a core component of the mitochondrial permeability transition pore (MPTP) and a key player in cell death. However, its role in camptothecin (CPT)-induced apoptosis has not been examined. We showed that CPT-induced apoptosis in QGY7703 cells and down-regulated the expression of ANT3. Using ANT3 knock-out and overexpression experiments, we provide further evidence that ANT3 plays a contributive role in CPT-induced apoptosis through induction of MPTP. We speculate that the down-regulation of ANT3 upon stimulation with CPT may be part of the molecular basis underlying the mechanism of acquired resistance to CPT."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2008.12.029"xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Guo X."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Hu Z."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Qiu L."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Guo C."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Yu Q."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/author | "Ying K."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/pages | "383-388"xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/title | "Down-regulation of adenine nucleotide translocase 3 and its role in camptothecin-induced apoptosis in human hepatoma QGY7703 cells."xsd:string |
http://purl.uniprot.org/citations/19111545 | http://purl.uniprot.org/core/volume | "583"xsd:string |
http://purl.uniprot.org/citations/19111545 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19111545 |
http://purl.uniprot.org/citations/19111545 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19111545 |
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http://purl.uniprot.org/uniprot/#_P12236-mappedCitation-19111545 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19111545 |
http://purl.uniprot.org/uniprot/#_Q59EI9-mappedCitation-19111545 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19111545 |
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http://purl.uniprot.org/uniprot/P12236 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19111545 |
http://purl.uniprot.org/uniprot/O75961 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19111545 |
http://purl.uniprot.org/uniprot/Q6I9V5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19111545 |