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http://purl.uniprot.org/citations/19111545http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19111545http://www.w3.org/2000/01/rdf-schema#comment"Adenine nucleotide translocase (ANT) is known as a core component of the mitochondrial permeability transition pore (MPTP) and a key player in cell death. However, its role in camptothecin (CPT)-induced apoptosis has not been examined. We showed that CPT-induced apoptosis in QGY7703 cells and down-regulated the expression of ANT3. Using ANT3 knock-out and overexpression experiments, we provide further evidence that ANT3 plays a contributive role in CPT-induced apoptosis through induction of MPTP. We speculate that the down-regulation of ANT3 upon stimulation with CPT may be part of the molecular basis underlying the mechanism of acquired resistance to CPT."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2008.12.029"xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Guo X."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Li J."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Hu Z."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Qiu L."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Guo C."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Zhang J."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Yu Q."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/author"Ying K."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/pages"383-388"xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/title"Down-regulation of adenine nucleotide translocase 3 and its role in camptothecin-induced apoptosis in human hepatoma QGY7703 cells."xsd:string
http://purl.uniprot.org/citations/19111545http://purl.uniprot.org/core/volume"583"xsd:string
http://purl.uniprot.org/citations/19111545http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19111545
http://purl.uniprot.org/citations/19111545http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19111545
http://purl.uniprot.org/uniprot/#_O75961-mappedCitation-19111545http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19111545
http://purl.uniprot.org/uniprot/#_P12236-mappedCitation-19111545http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19111545
http://purl.uniprot.org/uniprot/#_Q59EI9-mappedCitation-19111545http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19111545
http://purl.uniprot.org/uniprot/#_Q6I9V5-mappedCitation-19111545http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19111545
http://purl.uniprot.org/uniprot/P12236http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19111545
http://purl.uniprot.org/uniprot/O75961http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19111545
http://purl.uniprot.org/uniprot/Q6I9V5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19111545