| http://purl.uniprot.org/citations/19132680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19132680 | http://www.w3.org/2000/01/rdf-schema#comment | "Cardiac conduction defects were found in transgenic mice deficient in urea transporter UT-B. To investigate the molecular mechanisms of the conduction defects caused by UT-B deletion, we studied the protein expression profiles of heart tissue (comprising most conduction system) in wild-type versus UT-B null mice at different ages. By two-dimensional electrophoresis-based comparative analysis, we found that more than dozen proteins were modulated (>two-fold) in the myocardium of UT-B null mice. Out of these modulated proteins, troponin T (TNNT2) presented significant changes in UT-B null mice at early stage prior to the development of P-R interval elongation, while the change of atrial natriuretic peptide (ANP) occurred only at late stage in UT-B null mice that had the AV block. These data indicate that UT-B deletion caused the dynamic expression regulation of TNNT2 and ANP, and these proteins may provide new clues to investigate the molecular events involved in cardiac conduction."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.org/dc/terms/identifier | "doi:10.1002/pmic.200701079"xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Chen G.Q."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Meng Y."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Zhou L."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Yu H."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Yang B."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Ji K."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Jin X."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Zhao L.J."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Wang L.S."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Zhao X.J."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/author | "Gao L.F."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/name | "Proteomics"xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/pages | "504-511"xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/title | "Differential protein expression in heart in UT-B null mice with cardiac conduction defects."xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/19132680 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19132680 |
| http://purl.uniprot.org/citations/19132680 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19132680 |
| http://purl.uniprot.org/uniprot/#_N0A5N9-mappedCitation-19132680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19132680 |
| http://purl.uniprot.org/uniprot/#_Q3TH80-mappedCitation-19132680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19132680 |
| http://purl.uniprot.org/uniprot/#_O55083-mappedCitation-19132680 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19132680 |