| http://purl.uniprot.org/citations/19140318 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19140318 | http://www.w3.org/2000/01/rdf-schema#comment | "In this study, we investigated trichostatin A (TSA), a histone deacetylase inhibitor, increased the Bone morphogenetic protein-2 (BMP-2) mRNA level in human osteoblasts line. Deletion analysis of the promoter region revealed that TSA-induced luciferase was regulated by the BMP-2 promoter spanning from -320 to-310. Electrophoresis mobility shift assay (EMSA) and Chromatin immunoprecipitation (CHIP) assay proved that this position was nuclear factor NF-kappaB responsive element. The results above demonstrated that acetylation plays a crucial role in BMP-2 expression and acetylation of NF-kappaB p65 and p50 subunits by TSA treatment may activate the BMP-2 promoter."xsd:string |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/author | "Bai X.Z."xsd:string |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/name | "Mol Biol (Mosk)"xsd:string |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/pages | "990-996"xsd:string |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/title | "[NF-kappaB modulates activation of the BMP-2 gene by trichostatin A]."xsd:string |
| http://purl.uniprot.org/citations/19140318 | http://purl.uniprot.org/core/volume | "42"xsd:string |
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