http://purl.uniprot.org/citations/19143842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19143842 | http://www.w3.org/2000/01/rdf-schema#comment | "The putative RNA-binding protein SUPPRESSOR OF GENE SILENCING 3 (SGS3) protects RNA from degradation before transformation into dsRNA by the RNA-dependent RNA polymerase RDR6 during plant post-transcriptional gene silencing and trans-acting small interfering (siRNA) pathways. In this study, we show that SGS3 acts as a homodimer, and that the point mutation sgs3-3 impairs post-transcriptional gene silencing in a dominant-negative manner through the formation of SGS3/sgs3-3 heterodimers. Unlike complete-loss-of-function sgs3 mutants, which are impaired in the accumulation of both micro RNA-directed TAS cleavage products and mature trans-acting siRNAs, the sgs3-3 mutant overaccumulates TAS cleavage products and exhibits slightly reduced trans-acting siRNA accumulation. Together, these results suggest that sgs3-3 is a neomorphic allele that shows increased RNA protective activity, resulting in decreased RNA processing by downstream post-transcriptional gene silencing and trans-acting siRNA pathway components."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1742-4658.2008.06828.x"xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/author | "Gy I."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/author | "Gissot L."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/author | "Adenot X."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/author | "Elmayan T."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/author | "Lauressergues D."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/author | "Vaucheret H."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/name | "FEBS J"xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/pages | "835-844"xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/title | "A neomorphic sgs3 allele stabilizing miRNA cleavage products reveals that SGS3 acts as a homodimer."xsd:string |
http://purl.uniprot.org/citations/19143842 | http://purl.uniprot.org/core/volume | "276"xsd:string |
http://purl.uniprot.org/citations/19143842 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19143842 |
http://purl.uniprot.org/citations/19143842 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19143842 |
http://purl.uniprot.org/uniprot/#_A0A1P8BE44-mappedCitation-19143842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19143842 |
http://purl.uniprot.org/uniprot/#_Q9SG02-mappedCitation-19143842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19143842 |
http://purl.uniprot.org/uniprot/#_Q9LDX1-mappedCitation-19143842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19143842 |
http://purl.uniprot.org/uniprot/Q9SG02 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19143842 |
http://purl.uniprot.org/uniprot/A0A1P8BE44 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19143842 |
http://purl.uniprot.org/uniprot/Q9LDX1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19143842 |