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http://purl.uniprot.org/citations/19146857http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19146857http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19146857http://www.w3.org/2000/01/rdf-schema#comment"Mutations in parkin gene are responsible for autosomal recessive Parkinson's disease (ARPD) and its loss-of-function is assumed to affect parkin ubiquitin ligase activity. Accumulation of its substrate may induce dopaminergic neurodegeneration in the substantia nigra (SN) of ARPD. Here, we show that parkin interacts with programmed cell death-2 isoform 1 (PDCD2-1) and promotes its ubiquitination. Furthermore, accumulation of PDCD2-1 was found in the SN of ARPD as well as in sporadic PD, suggesting that common failure of the ubiquitin-proteasome system is associated with neuronal death in both ARPD and sporadic PD."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2008.12.055"xsd:string
http://purl.uniprot.org/citations/19146857http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2008.12.055"xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Mori H."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Mori H."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Sharp P.A."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Sharp P.A."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Sato K."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Sato K."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Sato S."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Sato S."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Mizuno Y."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Mizuno Y."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Hattori N."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Hattori N."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Shiba K."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Shiba K."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Fukae J."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/author"Fukae J."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/19146857http://purl.uniprot.org/core/name"FEBS Lett."xsd:string