| http://purl.uniprot.org/citations/19148225 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19148225 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19148225 | http://www.w3.org/2000/01/rdf-schema#comment | "Ubiquilins (UBQLNs) are adaptor proteins thought to deliver ubiquitinated substrates to proteasomes. Here, we show a role for UBQLN in autophagy: enforced expression of UBQLN protects cells from starvation-induced death, whereas depletion of UBQLN renders cells more susceptible. The UBQLN protective effect requires the autophagy-related genes ATG5 and ATG7, two essential components of autophagy. The ubiquitin-associated domain of UBQLN mediates both its association with autophagosomes and its protective effect against starvation. Depletion of UBQLN delays the delivery of autophagosomes to lysosomes. This study identifies a new role for UBQLN in regulating the maturation of autophagy, expanding the involvement of ubiquitin-related proteins in this process."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2008.238"xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2008.238"xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Brown E.J."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Brown E.J."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Morisaki H."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Morisaki H."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Debnath J."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Debnath J."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "N'Diaye E.N."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "N'Diaye E.N."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Kajihara K.K."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Kajihara K.K."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Hsieh I."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/author | "Hsieh I."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/pages | "173-179"xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/pages | "173-179"xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/title | "PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation."xsd:string |
| http://purl.uniprot.org/citations/19148225 | http://purl.uniprot.org/core/title | "PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation."xsd:string |