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http://purl.uniprot.org/citations/19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19148489http://www.w3.org/2000/01/rdf-schema#comment"We previously reported the SART3 gene to be a tumor-rejection antigen gene encoding a peptide at positions 109-118 (SART3(109-118)) with the ability to induce HLA-A24-restricted cytotoxic T lymphocytes. In this study, we investigated both humoral and cellular responses to this peptide in cancer patients with alleles other than HLA-A24 to explore the possibility of using this peptide as a cancer vaccine for these patients. IgG reactive to SART3(109-118) peptide was identified in sera of the vast majority of non-cancer subjects (n=50) and all cancer patients (n=50) tested without apparent HLA-A association. Levels of anti-SART3(109-118) peptide antibody in cancer patients were significantly higher than those of non-cancer subjects, but no difference was found between HLA-A24+A2- and HLA-A24-A2+ cancer patients. This peptide induced cancer cell-reactive cytotoxic T lymphocytes from peripheral blood mononuclear cells of both healthy donors and prostate cancer patients with HLA-A11, HLA-A31 and HLA-A33 alleles, but not with HLA-A2. These results suggest that this peptide can be applicable as a cancer vaccine not only for HLA-A24+, but also for HLA-A11+, HLA-A31+ and HLA-A33+ prostate cancer patients."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Itoh K."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Niu Y."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Naito M."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Shichijo S."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Noguchi M."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Komatsu N."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Terasaki Y."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Gohara S."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/author"Mohamed E.R."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/name"Int J Oncol"xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/pages"529-536"xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/title"Capability of SART3(109-118) peptide to induce cytotoxic T lymphocytes from prostate cancer patients with HLA class I-A11, -A31 and -A33 alleles."xsd:string
http://purl.uniprot.org/citations/19148489http://purl.uniprot.org/core/volume"34"xsd:string
http://purl.uniprot.org/citations/19148489http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19148489
http://purl.uniprot.org/citations/19148489http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19148489
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489
http://purl.uniprot.org/uniprot/#_A0A0G2R0N3-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489
http://purl.uniprot.org/uniprot/#_A0A0G2R0N4-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489
http://purl.uniprot.org/uniprot/#_A0A0G2R0N5-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489
http://purl.uniprot.org/uniprot/#_A0A076JXB7-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489
http://purl.uniprot.org/uniprot/#_A0A076L0P9-mappedCitation-19148489http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19148489