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http://purl.uniprot.org/citations/19154205http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19154205http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19154205http://www.w3.org/2000/01/rdf-schema#comment"Arabidopsis thaliana is known to produce the phytoalexin camalexin in response to abiotic and biotic stress. Here we studied the mechanisms of tolerance to camalexin in the fungus Botrytis cinerea, a necrotrophic pathogen of A. thaliana. Exposure of B. cinerea to camalexin induces expression of BcatrB, an ABC transporter that functions in the efflux of fungitoxic compounds. B. cinerea inoculated on wild-type A. thaliana plants yields smaller lesions than on camalexin-deficient A. thaliana mutants. A B. cinerea strain lacking functional BcatrB is more sensitive to camalexin in vitro and less virulent on wild-type plants, but is still fully virulent on camalexin-deficient mutants. Pre-treatment of A. thaliana with UV-C leads to increased camalexin accumulation and substantial resistance to B. cinerea. UV-C-induced resistance was not seen in the camalexin-deficient mutants cyp79B2/B3, cyp71A13, pad3 or pad2, and was strongly reduced in ups1. Here we demonstrate that an ABC transporter is a virulence factor that increases tolerance of the pathogen towards a phytoalexin, and the complete restoration of virulence on host plants lacking this phytoalexin."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-313x.2009.03794.x"xsd:string
http://purl.uniprot.org/citations/19154205http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-313x.2009.03794.x"xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Metraux J.P."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Metraux J.P."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Buchala A."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Buchala A."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Hahn M."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Hahn M."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Kretschmer M."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Kretschmer M."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Mosbach A."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Mosbach A."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Abou-Mansour E."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Abou-Mansour E."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Bochet C.G."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Bochet C.G."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Schoonbeek H.J."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Schoonbeek H.J."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Stefanato F.L."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/author"Stefanato F.L."xsd:string
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19154205http://purl.uniprot.org/core/date"2009"xsd:gYear