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http://purl.uniprot.org/citations/19158662 | http://www.w3.org/2000/01/rdf-schema#comment | "Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is needed for retrograde membrane trafficking from lysosomal and late endosomal compartments and its synthesis is tightly regulated. But how cells regulate PtdIns(3,5)P2 synthesis--for example, in response to hyperosmotic shock--remains unexplained. A paper from the Weisman group gives the most complete picture so far of a multiprotein complex that controls PtdIns(3,5)P2 synthesis and explains how a VAC14 mutation functionally impairs the scaffold protein at the heart of the complex and causes a neurodegenerative condition in mice."xsd:string |
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http://purl.uniprot.org/citations/19158662 | http://purl.uniprot.org/core/author | "Dove S.K."xsd:string |
http://purl.uniprot.org/citations/19158662 | http://purl.uniprot.org/core/author | "Michell R.H."xsd:string |
http://purl.uniprot.org/citations/19158662 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19158662 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
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http://purl.uniprot.org/citations/19158662 | http://purl.uniprot.org/core/title | "A protein complex that regulates PtdIns(3,5)P2 levels."xsd:string |
http://purl.uniprot.org/citations/19158662 | http://purl.uniprot.org/core/volume | "28"xsd:string |
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