http://purl.uniprot.org/citations/19160485 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19160485 | http://www.w3.org/2000/01/rdf-schema#comment | "The Myc-associated zinc-finger protein, Miz1, is a negative regulator of cell proliferation and induces expression of the cell-cycle inhibitors p15(Ink4b) and p21(Cip1). Here we identify the ribosomal protein L23 as a negative regulator of Miz1-dependent transactivation. L23 exerts this function by retaining nucleophosmin, an essential co-activator of Miz1 required for Miz1-induced cell-cycle arrest, in the nucleolus. Mutant forms of nucleophosmin found in acute myeloid leukaemia fail to co-activate Miz1 and re-localize it to the cytosol. As L23 is encoded by a direct target gene of Myc, this regulatory circuit may provide a feedback mechanism that links translation of Myc target genes and cell growth to Miz1-dependent cell-cycle arrest."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncb1764"xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/author | "Pelicci P.G."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/author | "Colombo E."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/author | "Eilers M."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/author | "Kleine-Kohlbrecher D."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/author | "Wanzel M."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/author | "Russ A.C."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/name | "Nat Cell Biol"xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/pages | "1051-1061"xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/title | "A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth."xsd:string |
http://purl.uniprot.org/citations/19160485 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/19160485 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19160485 |
http://purl.uniprot.org/citations/19160485 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19160485 |
http://purl.uniprot.org/uniprot/P01106#attribution-52504966ED4570A91358EACB6611E310 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/P06748#attribution-52504966ED4570A91358EACB6611E310 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/P06748#attribution-7D79C0700707DAF32EC8D5BA09D2A5C6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/Q61937#attribution-DCCBB070FFDC8E9C050BAB3473BCC86C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/P62829#attribution-52504966ED4570A91358EACB6611E310 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/P62829#attribution-7D79C0700707DAF32EC8D5BA09D2A5C6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/P62829#attribution-DCCBB070FFDC8E9C050BAB3473BCC86C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/Q13105#attribution-52504966ED4570A91358EACB6611E310 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |
http://purl.uniprot.org/uniprot/Q13105#attribution-7D79C0700707DAF32EC8D5BA09D2A5C6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19160485 |