| http://purl.uniprot.org/citations/19166301 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19166301 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19166301 | http://www.w3.org/2000/01/rdf-schema#comment | "Adaptation to vertebrate blood feeding includes development of a salivary "magic potion" that can disarm host hemostasis and inflammatory reactions. Within the lower Diptera, a vertebrate blood-sucking mode evolved in the Psychodidae (sand flies), Culicidae (mosquitoes), Ceratopogonidae (biting midges), Simuliidae (black flies), and the frog-feeding Corethrellidae. Sialotranscriptome analyses from several species of mosquitoes and sand flies and from one biting midge indicate divergence in the evolution of the blood-sucking salivary potion, manifested in the finding of many unique proteins within each insect family, and even genus. Gene duplication and divergence events are highly prevalent, possibly driven by vertebrate host immune pressure. Within this framework, we describe the sialome (from Greek sialo, saliva) of the black fly Simulium vittatum and discuss the findings within the context of the protein families found in other blood-sucking Diptera. Sequences and results of Blast searches against several protein family databases are given in Supplemental Tables S1 and S2, which can be obtained from http://exon.niaid.nih.gov/transcriptome/S_vittatum/T1/SV-tb1.zip and http://exon.niaid.nih.gov/transcriptome/S_vittatum/T2/SV-tb2.zip ."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.org/dc/terms/identifier | "doi:10.1021/pr8008429"xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.org/dc/terms/identifier | "doi:10.1021/pr8008429"xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Ribeiro J.M."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Ribeiro J.M."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Meng Z."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Meng Z."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Andersen J.F."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Andersen J.F."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Champagne D.E."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Champagne D.E."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Pham V.M."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/author | "Pham V.M."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/name | "J. Proteome Res."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/name | "J Proteome Res"xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/pages | "1474-1488"xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/pages | "1474-1488"xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/title | "Insight into the sialome of the Black Fly, Simulium vittatum."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/title | "Insight into the sialome of the Black Fly, Simulium vittatum."xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/19166301 | http://purl.uniprot.org/core/volume | "8"xsd:string |